postmortem human brain tissue samples (Johns Hopkins HealthCare)
90
Structured Review
Johns Hopkins HealthCare
postmortem human brain tissue samples
Postmortem Human Brain Tissue Samples, supplied by Johns Hopkins HealthCare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/postmortem+human+brain+tissue+samples/tc+1+cells/pm37365312-397-17-8
Average 90 stars, based on 1 article reviews
Postmortem Human Brain Tissue Samples, supplied by Johns Hopkins HealthCare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/postmortem+human+brain+tissue+samples/tc+1+cells/pm37365312-397-17-8
Average 90 stars, based on 1 article reviews
postmortem human brain tissue samples - by Bioz Stars,
2026-09
90/100 stars
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other:Article Title: Globally reduced N 6 -methyladenosine (m 6 A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration. Article Snippet: Repeat expansion in C9ORF72 is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).. Here we show that N 6 -m et hy la denosine (mA), the most prevalent internal mRNA modification, is downregulated in C9ORF72-ALS/FTD patient-derived induced pluripotent stem cell (iPSC)-differentiated neurons and postmortem brain tissues.. The global mA h yp om et hy lation leads to transcriptome-wide mRNA stabilization and upregulated gene expression, particularly for genes involved in synaptic activity and neuronal function. |